William A Weiss Selected Research

Aurora Kinase A

1/2024	Aurora Kinase A inhibition enhances DNA damage and tumor cell death with 131I-MIBG therapy in high-risk neuroblastoma.
1/2021	The synergy of BET inhibitors with aurora A kinase inhibitors in MYCN-amplified neuroblastoma is heightened with functional TP53.

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William A Weiss Research Topics

Disease

90	Neoplasms (Cancer) 03/2024 - 08/2002
30	Medulloblastoma 10/2023 - 12/2006
30	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 01/2005
27	Neuroblastoma 03/2024 - 09/2003
26	Glioma (Gliomas) 11/2021 - 12/2003
8	Carcinogenesis 03/2024 - 09/2003
7	Neoplasm Metastasis (Metastasis) 01/2023 - 07/2013
6	Breast Neoplasms (Breast Cancer) 01/2022 - 12/2007
6	Brain Neoplasms (Brain Tumor) 01/2019 - 02/2004
6	Astrocytoma (Pilocytic Astrocytoma) 04/2013 - 01/2005
3	Oligodendroglioma 12/2010 - 04/2003
2	Retinoblastoma (Glioblastoma, Retinal) 01/2014 - 06/2008
1	Genomic Instability 10/2023
1	Adenocarcinoma of Lung 11/2022
1	Neurodevelopmental Disorders 01/2021

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 01/2023 - 09/2003
14	Phosphotransferases (Kinase)IBA 01/2020 - 08/2002
12	ErbB Receptors (EGF Receptor)IBA 01/2020 - 04/2003
9	Biomarkers (Surrogate Marker)IBA 11/2022 - 10/2002
8	epidermal growth factor receptor VIIIIBA 01/2020 - 05/2012
7	LigandsIBA 01/2023 - 10/2007
6	Transcription Factors (Transcription Factor)IBA 08/2023 - 08/2006
6	Temozolomide (Temodar)FDA LinkGeneric 01/2018 - 03/2009
5	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2017 - 08/2006
5	TOR Serine-Threonine KinasesIBA 01/2014 - 01/2009
5	Small Interfering RNA (siRNA)IBA 01/2012 - 01/2005
5	PI103IBA 01/2012 - 05/2006
4	N-Myc Proto-Oncogene ProteinIBA 01/2024 - 08/2006
4	3-Iodobenzylguanidine (Iobenguane)IBA 01/2024 - 09/2010
4	Phosphoric Monoester Hydrolases (Phosphatases)IBA 10/2023 - 07/2013
4	ChromatinIBA 08/2023 - 01/2017
4	MTOR InhibitorsIBA 01/2022 - 01/2012
4	Sirolimus (Rapamycin)FDA Link 01/2018 - 09/2007
4	Mechanistic Target of Rapamycin Complex 1IBA 01/2018 - 05/2011
3	Oncogene Proteins (Oncogene Protein)IBA 11/2022 - 01/2016
3	RapaLink-1IBA 01/2022 - 01/2017
3	NucleotidesIBA 11/2021 - 10/2019
3	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2019
3	TensinsIBA 01/2019 - 11/2010
3	CytokinesIBA 01/2019 - 07/2013
3	LipidsIBA 01/2019 - 07/2012
3	EnzymesIBA 01/2019 - 05/2006
3	Radiation-Sensitizing AgentsIBA 01/2018 - 07/2011
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2017 - 10/2007
3	PLX 4720IBA 09/2015 - 12/2011
3	DNA (Deoxyribonucleic Acid)IBA 09/2014 - 08/2011
3	dactolisibIBA 01/2012 - 11/2010
3	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2012 - 12/2006
3	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 10/2007 - 08/2006
3	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 10/2006 - 12/2003
2	Aurora Kinase AIBA 01/2024 - 01/2021
2	Monoclonal AntibodiesIBA 01/2022 - 07/2013
2	Ku 0063794IBA 01/2020 - 01/2012
2	Lysine (L-Lysine)FDA Link 01/2019 - 03/2013
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2018 - 01/2018
2	gamma-Aminobutyric Acid (GABA)IBA 11/2018 - 11/2014
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2018 - 07/2012
2	ParaffinIBA 01/2016 - 03/2014
2	Formaldehyde (Formol)FDA Link 01/2016 - 03/2014
2	Ion Channels (Ion Channel)IBA 09/2015 - 08/2012
2	Protein Kinases (Protein Kinase)IBA 01/2015 - 08/2002
2	MicroRNAs (MicroRNA)IBA 07/2013 - 06/2008
2	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 12/2012 - 04/2011
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 05/2012 - 09/2007
2	Histone Deacetylase InhibitorsIBA 07/2011 - 04/2011
2	Vorinostat FDA Link 07/2011 - 04/2011
2	Chloroquine (Aralen)FDA LinkGeneric 05/2011 - 11/2010
2	Caspase 3 (Caspase-3)IBA 11/2008 - 12/2007
1	Anaplastic Lymphoma KinaseIBA 03/2024
1	Adrenergic Agents (Adrenergic Drugs)IBA 03/2024
1	MLN 8237IBA 01/2024
1	RadiopharmaceuticalsIBA 01/2024
1	Eukaryotic Initiation Factor-4EIBA 01/2023
1	RNA-Binding Proteins (RNA-Binding Protein)IBA 11/2022
1	AcyltransferasesIBA 11/2022
1	dabrafenibIBA 11/2022
1	trametinibIBA 11/2022
1	CateninsIBA 11/2022
1	TetraspaninsIBA 01/2022
1	Drug CombinationsIBA 01/2022
1	CalreticulinIBA 01/2022
1	Tyrosine (L-Tyrosine)FDA Link 11/2021
1	AntigensIBA 01/2021
1	Untranslated RNA (Noncoding RNA)IBA 01/2021
1	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	monoclonal antibody 806IBA 01/2020
1	PP242IBA 01/2020
1	sapanisertibIBA 01/2020
1	depatuxizumab mafodotinIBA 01/2020
1	Tyrosine Kinase InhibitorsIBA 01/2020
1	ABT-414IBA 01/2020
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2020
1	BetacellulinIBA 01/2020

Therapy/Procedure

64	Therapeutics 01/2024 - 10/2002
7	Drug Therapy (Chemotherapy) 11/2016 - 06/2008
3	Immunotherapy 01/2022 - 11/2016
2	Radiotherapy 01/2024 - 02/2015
2	Transplantation 01/2019 - 05/2012
1	Ligation 01/2022